We investigate temperate rainforest responses to climate and disturbance regimes since similar to 7 ka on the Andean foothills of the Estuario Reloncav & iacute; sector of the Chilean Lake District, using a decadally resolved record from Lago Campanario. Our results show mixed temperate rainforests with dominance of Valdivian Rainforest assemblages between similar to 6.8-3 ka followed by a gradual transition toward North Patagonian Rainforest-dominated assemblages from similar to 3 ka to the present. This trend is overprinted by centennial-scale fluctuations, most intensely developed between similar to 2-0.3 ka. We interpret relatively warm/dry conditions between similar to 6.8-5 ka followed by a multimillennial trend toward cool-temperate/humid conditions until the present. Large-magnitude hydroclimate changes at centennial timescale prevailed between similar to 2-0.3 ka, culminating with cool-temperate/humid conditions and subsequent Chilean/European disturbance. Fire activity was predominantly low and punctuated by discrete increases, the largest of which occurred between similar to 5.6-5.5 ka and similar to 1.4-0.6 ka. Tephra layers attest to explosive volcanism with multiple events clustered between similar to 6.2-6.1 ka, similar to 3.5-2.5 ka, and similar to 1.4-0.9 ka. Significant rates-of-change scores at similar to 5.7 ka, similar to 1.3 ka, and between similar to 0.7-0.3 ka document abrupt vegetation changes following fire episodes and explosive volcanic events. We interpret invigoration of the southern westerlies since similar to 7 ka overprinted by centennial-scale variability that promoted fires during warm/dry anomalies. Fires and explosive volcanism, aided by pre-Columbian (<= 1.4 ka) and historical human burning (<= 0.2 ka), catalyzed vegetation responses to climate change promoting the proliferation of fast-growth shade-intolerant taxa. Disturbance during relatively warm/dry intervals favored the rainforest trees Eucryphia/Caldcluvia and Weinmannia trichosperma, whereas cool-temperate/humid intervals favored Nothofagus and Poaceae.